- Sand Gravel & Aggregate, Wolfville
- Sandwich Shop Restaurants, Wolfville
- Secondary Schools, Wolfville
- Security Brokers & Dealers, Wolfville
- Septic Systems Installation & Repair, Wolfville
- Septic Tanks & Septic Systems Contractors, Wolfville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Shoe Stores, Wolfville - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Wolfville
- Sightseeing Tours, Wolfville
- Silos & Equipment, Wolfville
- Sleds, Snowboards & Snowshoes Shops, Wolfville - Snow Sleds, Toboggans, Helmets, Boots, Goggles, Clothing, Gear & More
- Small Business Services, Wolfville
- Snow Removal Services, Wolfville - Snow Plow Service
- Social Services & Welfare, Wolfville
- Societies & Foundation Associations, Wolfville
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- Sod & Sodding Service, Wolfville
- Special Events Photographers, Wolfville
- Special Interest Schools Or Instruction, Wolfville
- Speciality Food Stores, Wolfville
- Specialty Animal Services, Wolfville
- Specialty Stores, Wolfville
- Speech & Hearing Specialists, Wolfville
- Speech Pathologists, Wolfville - Speech & Language Therapy
- Sporting Goods Equipment Rental, Wolfville
- Sporting Goods Stores, Wolfville
- Stitching Services, Wolfville
- Stock & Bond Brokers & Dealers, Wolfville
- Stocks & Bond Brokers, Wolfville
- Substance Abuse Outpatient Clinics, Wolfville
- Swimming Pools, Wolfville
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